Журнал «Боль. Суставы. Позвоночник» 1 (21) 2016
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Structural and functional state of bone and fracture risk in patients with atherosclerosis of coronary vessels
Авторы: Kordubailo I.A. - Institute of Gerontology named after D.F. Chebotarev NAMS of Ukraine, Kyiv, Ukraine; Leoshko I.V., Nishkumay O.I. - Bogomolets National Medical University, Kyiv, Ukraine; Lysak Z.V. - Alexander Hospital Kyiv, Kyiv, Ukraine
Рубрики: Ревматология, Травматология и ортопедия
Разделы: Медицинские форумы
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The article was published on p. 75
Introduction. According to WHO experts, osteoporosis and coronary heart disease occupies a leading place in the structure of morbidity and mortality. Results of studies in recent years indicate the presence of common pathogenetic mechanisms that lead to the development of osteoporosis and atherosclerosis. So, the study of the factors that may influence the increase of risk of fractures in patients with established atherosclerosis, their prompt correction is important in our modern medicine.
The aim is to study changes in the structural and functional state of the bone tissue in patients with diagnosed coronary atherosclerosis and to analyze risk factors of bone fractures.
Materials and methods. The study was conducted in terms of student scientific society of the Department of Internal Medicine № 2 Bogomolets National Medicine University. The survey of 21 patients with coronary atherosclerosis which was diagnosed according to coronaroventriculography was conducted coronary atherosclerosis. In order to identify risk factors for fracture technique FRAX (fracture risk assessment tool) was determed. General laboratory methods included the determination of lipid metabolism. Study of structural and functional state of the bone was conducted with the help of an ultrasonic densytometer «Achilles» + «Lunar» (USA).
Results. The positive correlation between the index of FRAX-1 and the level of total cholesterol and FRAX-2 and total cholesterol levels was revealed.
Conclusions. The investigations indicate the need for early densitometry of surveys and questionnaires in patients with established coronary atherosclerosis, hypercholesterolemia, for the prevention of bone fractures.